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23 May 2019

The European Lead Factory welcomes new innovative screening proposals

The European Lead Factory is excited to continue running high quality programmes and is looking forward to receiving more innovative screening proposals.

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02 May 2019

The success story continues: new funding for the European Lead Factory

The European Lead Factory (ELF) secured a total project budget of EUR 36.5 million under the second framework of the Innovative Medicines Initiative (IMI). 20 partners in 7 countries will push forward the transformation of potential drug targets to new medicines in the new project ESCulab (European Screening Centre: unique library for attractive biology) under the European Lead Factory brand.

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02 May 2019

The European Lead Factory, Europe’s largest collaborative drug discovery platform, continues its success story

2 May 2019, Utrecht (The Netherlands) The European Lead Factory (ELF) secured a total project budget of EUR 36.5 million under the second framework of the Innovative Medicines Initiative (IMI). Over the next 5 years, 20 partners in 7 countries will push forward the transformation of potential drug targets to new medicines in the new project ESCulab (European Screening Centre: unique library for attractive biology) under the European Lead Factory brand.

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14 February 2019

Seeding tomorrow’s priority medicines

The European Lead Factory has successfully accelerated the process of drug discovery. A recently published public summary of results so far clearly shows the benefits of collaborative drug discovery in the European arena.

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24 October 2018

EU Lead Factory wins Best IMI Communication Product Award

Yesterday the European Lead Factory animation won the best Innovative Medicines Initiative (IMI) Communication Product Award. The awards were handed out as part of IMI’s 10th anniversary during the IMI Scientific Symposium in Brussels.

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24 September 2018

Keapstone Therapeutics secures further €1,1 million investment from Parkinson’s UK

Keapstone Therapeutics is preparing to make the next steps in clinical candidate selection and first-in-human studies. This investment brings the total seed investment to € 2,4 million. Last year Parkinson’s UK together with Sheffield University launched the virtual biotech Keapstone Therapeutics to further develop compounds that boost the internal cellular defence mechanisms against oxidative stress to combat neurogenerative diseases. These compounds were discovered by IMI’s European Lead Factory. 

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26 July 2018

The European Lead Factory contributing to the fight against Alzheimer's

The key goal of ELF is to create validated hit series. Another successful ELF programme aimed at identifying small molecules for the treatment of Alzheimer’s Disease has culminated in the most potent compound yet identified by the ELF team at Newhouse, Scotland with the most active compound reaching 100pM. These compounds also have excellent physicochemical properties.

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10 July 2018

High number of SMEs benefit greatly from the European Lead Factory

The European Lead Factory is remarkably attractive for SMEs. The consortium consists of 30 partners, of which 10 are SMEs. They perform the screening and help to translate innovative design ideas into industry‐standard compound libraries. ELF is also interacting with a high number of SMEs who have enrolled via the target crowdsourcing route with in total 25 programmes (out of 88 programmes in the portfolio).

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07 June 2018

European Lead Factory reaches milestone of 200,000 novel compounds

Within a period of five years, the European Lead Factory (ELF) has reached one of its goals by completing the Public Compound Collection (PCC), comprising a commendable total of 200,000 novel compounds. The library production partners collaborated closely with the academic groups within ELF to reach this goal. The pan-European Public Chemistry Consortium is duly celebrating the achievement of this challenging objective.

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08 May 2018

Successful Stakeholder Meeting boosts energy for future collaborative drug discovery

On 16 and 17 April 2018 the European Lead Factory (ELF) Target Owner Workshop and Stakeholder Meeting took place in the heart of Europe, Brussels. An exciting row of speakers allowed for a retrospect on five years of successfully seeding and nursing innovative drug discovery projects. It also gave a hint about the future and how we can further grow the successful ELF platform to serve drug discovery for priority medicines.

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